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Doctors prescribe Amoxicillin for different types of bacterial infections. However, the penicillin-type antibiotic will not work on infections like the flu, the common cold, or other viral infections. Amoxicillin comes with different brand names like Amoxil, Dispermox, Wymox, Polymox, Trimox, or Larotid. Patients can ingest it orally since it comes in tablets, capsules, and suspension for children.

Uses of Amoxicillin

Amoxicillin is commonly used in the treatment of the following infections:

  • Bronchitis
  • Tonsillitis
  • Pneumonia
  • Ear, nose, and  throat (ENT) infections
  • Certain types of skin infections
  • Urinary tract infections

The drug https://berkshireorthopaedics.com/prednisone.php is also combined with other drugs, such as clarithromycin and lansoprazole, to treat Helicobacter pylori infection of the stomach.

How to Use Amoxicillin Oral

The leaflet in the Amoxicillin pack contains information about the drug. However, depending on your health condition, your physician or pharmacist will advise on the best way to use it. You should consume the drug with or without food within an interval of 8 -12 hours and at the same time each day to ensure maximum effectiveness. 

Before administering the suspension to pediatrics, ensure to shake it vigorously before use. You can also mix it with milk, baby formula, or juice. But it is best to use the measuring device provided by the manufacturer to administer the correct dose. 

While chewable tablets must be chewed before swallowing, the regular ones should be swallowed whole with an adequate amount of water. 

You should read the medication guidelines provided if you are taking Amoxicillin in combination with other drugs for the treatment of GIT ulcers.

Amoxicillin Dosing Information 

Amoxicillin dosage is based on your doctor's assessment of how severe the infection is and your weight or age. There is also a dose modification for people with renal impairment. However, we will provide a general dosage guide for this drug.

Dosage for Treatment of Infections of the Ear, Throat, Nose, Skin, and Genitourinary Tract 

The usual adult dose for mild to moderate infection is 500 milligrams every twelve hours or 250 milligrams every eight hours for 72 hours. However, the adult dose for severe infection is 500 mg every 8 hours for at least 5 days.

In children > 3 years, the dosage for mild to moderate infection is 25 mg/kg every twelve hours or 20 mg/kg every eight hours daily in divided doses. 

The dosage for severe infection in children > 3 years is either 45 mg/kg every twelve hours or 40 mg/kg every eight hours daily in divided doses.

Dosage for Treatment of Lower Respiratory Tract Infection 

The dosage in adults and children is 500 milligrams every eight hours and 40 mg/kg every eight hours in divided doses respectively. 

Dosage for H. pylori Treatment 

In conjunction with clarithromycin and lansoprazole, 1 gram of Amoxicillin is administered every 12 hours for 14 days. 

Dosage for Chlamydia

You should ingest 500 millgrams of Amoxicillin tablets every eight hours for seven days.

Precautions 

Before using this drug, inform your doctor if you have allergies to penicillin or Cephalosporins. Also inform your doctor if you have any history of:

  • Infectious mononucleosis
  • Kidney impairment
  • Diarrhea due to antibiotics use
  • Recent typhoid vaccination
  • Hormonal birth control pills

Do well to let your doctor know if you are pregnant or planning to get pregnant. Amoxicillin can be excreted into the breast milk, inform your doctor if you are breastfeeding before taking it.

Side Effects of Amoxicillin

The common side effects associated with use of this drug are: nausea, diarrhea, vomiting, or rashes. However, you may need to inform your doctor if you experience signs such as: 

  • difficulty breathing
  • hives
  • severe skin reactions
  • fever
  • skin discoloration 
  • burning eyes  
  • swelling in your throat or face
  • severe stomach pain 

Other side effects that may occur due to prolonged use of this drug for repeated periods of time include:

  • Oral thrush
  • Vaginal yeast infections
  • Changes in vaginal discharge
  • Loss of appetite
  • Symptoms of liver impairment
  • Bloody stool with or without mucus
  • Clostridium difficile disturbances

You can contact your doctor if you have concerns about the drug or experience any strange effects.

Missed Doses and Overdose

Do not attempt to take more than the recommended dose if you have missed a dose. It may result in an overdose, which could become toxic to your body. Waiting until your next dosing time is highly recommended, but you should inform your doctor about any incidences of missed dose. In case of overdose or poisoning, contact the poison control center in your area. 

Interactions

Amoxicillin interacts with over 30 drugs and 6 disease conditions.

The disease conditions include:

  • Phenylketonuria (PKU)
  • Colitis
  • Hemodialysis
  • Diabetes
  • Kidney dysfunction
  • Mononucleosis

The major drug interactions of Amoxicillin are with the following drugs:

  • Cholera live vaccine
  • BCG
  • Mycophenolic acid
  • Methotrexate
  • Mycophenolate mofetil
  • Typhoid vaccine live

Storage

Amoxicillin tablets should be stored at room temperature away from moisture. The suspension should be refrigerated between 2-8 °C. All medicines should be kept out of the reach of children and pets.